SIR-Spheres Colon Cancer Treatment

sirt colon cancer treatment mainline paAt the PA Vascular Institute, we’re here to advise our patients throughout the Mainline, Lehigh Valley, PA, about SIR-Spheres colon cancer treatment. We utilize cutting-edge technology to aid our patients and make treatments as comfortable as possible with fast recovery rates, so they can quickly return to their regular activities and lifestyle.

Colorectal cancer, also known as bowel cancer or colon cancer, is the growth of cancer cells in the colon or rectum – parts of the large intestine. Cancer is the irregular development of cells that contain the ability to invade and spread to other parts of the body. Some signs and symptoms of colon cancer may include blood in the stool, a change in bowel movements, weight loss, and constant tiredness. Colorectal cancer normally begins as a benign tumor, usually in the form of a polyp, which can become cancerous over time.


A majority of colorectal cancers develop because of old age and lifestyle factors, while only a small percentage of cases come about because of underlying genetic disorders. Some risk factors include poor diet, obesity, cigarette smoking, and a lack of physical activity. Dietary factors that are shown to worsen the risk include eating large quantities of red and processed meat as well as drinking alcohol. Another factor that puts people at risk is having an inflammatory bowel disease such as Crohn’s disease or ulcerative colitis.


Selective internal radiation therapy (SIRT) is a form of radiation therapy used in interventional radiology for the treatment of colorectal cancer, usually after it has spread to the liver. This form of therapy is often used in conjunction with chemotherapy for optimal results.

SIRT includes injecting tiny microspheres of radioactive material inside the arteries that are supplying the tumor. SIR-Spheres microspheres consist of resin-based microspheres with an average diameter of somewhere between 20 and 60 micrometers. These microspheres are impregnated with Y-90, which is used to decrease the size of a tumor.

After Y-90 is injected into the hepatic artery through a catheter, the microspheres lodge into the vasculature of the tumor. The radiation will result in tumor tissue damage and hopefully, the complete eradication of the tumor. Due to the half-life, a majority of the radiation is administered within two weeks. After a month has passed, almost no radioactivity should remain.

This treatment is known to increase the length of time that the colorectal cancer is stable, without adversely affecting the quality of life.

Here at the PA Vascular Institute, we serve patients in the Mainline and Lehigh Valley, PA. If you’re looking to learn more about IVC placement, therasphere treatment or SIR-Spheres colon cancer treatment, please contact us as soon as possible. We understand how difficult it is to be diagnosed with cancer. That is why we use cutting-edge technology that has you returning to your normal activities and everyday life as soon as possible.

To learn more about SIR-spheres colon cancer treatment, give our team at PA Vascular Institute a call today.